Volume 44, No 4, 1999 December Leading articles 151 Human genome project: Implications for medical science. Eric H Karunanayake 156 An effective and affordable cervical carcinoma screening programme for Sri Lanka. Marian Priyanthi Kumarasinghe 159 Genital warts. Sujatha Samarakoon Papers 162 Developing a molecular marker for metachronous colorectal cancer. WMM de Silva 166 Thyroid function in thalassaemia major. Manouri P Senanayake, SAIK Suraweera, HDM Hubert 169 Severe systemic effects of Merrem's hump-nosed viper bite. SAM Kularatne, Neelakanthi Ranatunga From the journals 171 RL Jayakody Case reports 173 A case of eosinophilic meningitis. AT Alibhoy, Bimsara Senanayake, MAH Fernando, HSU Amarasekera, JC Wijesekera 175 Kimura's disease in a Sri Lankan man. Neelakanthi Ratnatunga, HWE Tissera 177 Neonatal herpes zoster infection. DRKC Jayawardene Personal views 179 Sleeping sickness strikes Sri Lanka. Saroj Jayasinghe 180 Cigarette smoking and anaesthesia. RH Gunawardana Letters 184 Heat stroke in young adults. MMD Fonseka 184 All that glitters in glitazones. K de Abrew, S Mylvaganam, MS Samarasekera 185 Re-emergence of measles. Sanath P Lamabadusuriya, Manouri Senanayake 186 Antipersonnel mines - a continuing threat to Sri Lankans in the new century. Gamini Goonetilleke 187 Intestinal helminth infections among children in a slum community in Enderamulla. WI Udayani, IK Uduwevidane, AL Uvais, SL Wanniarachchi, SN Warnakulasuriya, NR de Silva 188 Methyldopa use should be restricted. HA de Silva, J Hewavisenthi, B Wijesiriwardena, MMD Fonseka 189 A sailor with a bubo. RSB Wickremesinghe 190 Successful desensitisation of allopurino-induced erythema multiforme. MMD Fonseka, H Sathischandra, SF Jayamanne, HJ de Silva 191 Conn's syndrome of Conn syndrome? SP Lamabadusuriya 192 Prostatic carcinoma in Sri Lanka - is it more common than cancer registry statistics? MVC de Silva, MS Fernando, SAS Goonewardene 193 Obituary